Overview:
A synthetic pentapeptide that selectively stimulates growth hormone (GH) secretion by acting as a ghrelin receptor (GHSR-1a) agonist. Unlike broader secretagogues, it does not significantly affect cortisol, prolactin, or ACTH levels. It has been the subject of published preclinical and clinical research examining its role in GH axis regulation and pituitary function.
Research areas include:
- Selective GHSR-1a agonism and downstream GH secretion
- Pulsatile growth hormone release and somatotroph function
- IGF-1 axis modulation and hepatic signaling
- Body composition research — lean mass and adipose tissue dynamics
- Sleep architecture and nocturnal GH pulse research
- Bone mineral density and connective tissue remodeling models
Compound Specifications
| Property | Value |
|---|---|
| CAS# | 170851-70-4 |
| Formula | C₃₈H₄₉N₉O₅ |
| Molecular Weight | 711.9 g/mol |
| Class | Synthetic pentapeptide GH secretagogue |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% HPLC |
| Storage | -20°C, protect from light |
| Reconstitution | Bacteriostatic water |
