Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH), consisting of the full 44-amino acid sequence of endogenous GHRH with a trans-3-hexenoic acid modification at the N-terminus. It has been the subject of extensive published clinical and preclinical research examining its role in growth hormone secretion and metabolic regulation.
Research areas include:
- GH/IGF-1 axis stimulation and downstream somatotropic signaling
- Visceral adipose tissue reduction and lipid metabolism research
- Hypothalamic-pituitary axis modulation
- Cognitive function and neuroprotective signaling in aging models
- Cardiovascular risk factor research in metabolic dysfunction models
Compound Specifications
| Property | Value |
|---|---|
| CAS# | 218949-48-5 |
| Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
| Molecular Weight | 5135.77 g/mol |
| Sequence | Trans-3-hexenoic acid-GHRH(1-44)-NH₂ |
| Appearance | White lyophilized powder |
| Purity | ≥99% HPLC |
| Storage | -20°C, protect from light |
| Reconstitution | Bacteriostatic water |
